Praziquantel is used to treat diseases in humans, mammals, and fish that are caused by infection with several types of internal/gastrointestinal, and external parasites including tapeworms, roundworms, nematodes, and trematodes/flukes. It is often effective with a single dose which can treat external and internal worms at the same time. It will not harm plants or stress fish. A large water change is not required. While Prazi is not temperature dependent, it is not advised to use any chemical when the water temperature is below 50 degrees F. Salt does not affect Prazi.
For use in Koi and goldfish ponds, Prazi is dissolved and placed in the pond, where it should be allowed to run through the filter and plumbing. The dosage is one gram of Prazi per 100 gallons.
The problem is that the stuff is tough to dissolve in water. Here are several techniques.
Prazi is often used with ProForm C©, and the usual system is to dissolve the Prazi in the last dose of ProForm C. Turns out that it's the formalin in the ProForm C that dissolves the Prazi. Some pond owners put the Prazi and some water in a sealed container, and shake it vigorously. It is said that all the Prazi still won't dissolve, but to just ignore it - it is safe to distribute around the pond.
Our own Duncan Griffiths (Instructor of K.O.I. #207 – Diagnosis and Treatment) did some research and testing, and came up a new formula. He calls it the 5+5+5 system. For a 5 gram treatment (500 gallons), add 5 grams of Prazi plus 5 ml of formaldehyde plus 5 ml of plain water. Mix to a free-flowing paste and leave for a few minutes to hydrate all the solids. Top off with water, stirring as you go. This should dissolve the Prazi 100%. Further dilute your mixture in a bucket of pond water and spread around the pond. For 1000 gallons, the formula would be 10+10+10, etc.
Please share how you dissolve it! Email email@example.com, and I’ll post responses here.